1-Ethyl-4-phenyl-1H-1,5-benzodiazepin-2(3H)-one

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Ethyl 2-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-1-yl)acetate

The seven-membered ring in the title compound, C(19)H(18)N(2)O(3), adopts a boat conformation with the two phenyl-ene C atoms representing the stern and the methyl-ene C atom the prow. The dihedral angle between the best plane through the seven-membered ring (r.m.s deviation = 0.343 Å) and the phenyl substituent is 31.9 (1)°. The dihedral angle between this best plane and the best plane through...

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4-Phenyl-1-(prop-2-yn-1-yl)-1H-1,5-benzodiazepin-2(3H)-one

4-Phenyl-1H-1,5-benzodiazepin-2(3H)-one reacts in the pres-ence of a concentrated aqueous solution of sodium hydroxide and a quaternary ammonium salt (as catalyst) in benzene (phase transfer catalysis) with propargyl bromide, affording the title benzodiazepine derivative, C(18)H(14)N(2)O. In the mol-ecule, the mean plane of the propargyl substituent is almost perpendicular with that of the amid...

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1-Allyl-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one

The seven-membered ring in the title compound, C(18)H(16)N(2)O, adopts a boat conformation with the two phenyl-ene carbons representing the stern and the methyl-ene C atom the prow. The dihedral angle between the best plane through the seven-membered ring and the phenyl ring is 62.13 (3)°.

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1-Acetyl-4-phenyl-5a,6,7,8,9,9a-hexa­hydro-5H-1,5-benzodiazepin-2(1H)-one

The seven-membered ring of the title compound, C(17)H(20)N(2)O(2), adopts an approximate boat conformation while the cyclo-hexyl ring adopts a chair conformation. In the crystal, adjacent mol-ecules are linked by N-H⋯O hydrogen bonds into a zigzag chain running along the c axis of the monoclinic unit cell.

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1-Phenyl-3H-2,3-benzodiazepin-4(5H)-one

The seven-membered ring in the title compound, C(15)H(12)N(2)O, adopts a boat-shaped conformation (with the methyl-ene C atom as the prow and the double-bond C=N pair of atoms as the stern). In the crystal, adjacent mol-ecules are linked by an N-H⋯O hydrogen bond to generate helical chains running along the a axis of the ortho-rhom-bic unit cell.

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ژورنال

عنوان ژورنال: IUCrData

سال: 2016

ISSN: 2414-3146

DOI: 10.1107/s2414314616006611